Alberto Marín-González

This study shows cohesin accelerates homology search in HR repair by transforming 3D diffusion into 1D scanning through loop extrusion and cohesion.

The paper shows that defective BRCA1-mediated DNA end resection leads to Group 1 tandem duplication formation and FANCM synthetic lethality in mouse models.

The paper shows cohesin-driven chromatin loop extrusion facilitates homology search during RAD51-mediated DNA repair in mammalian cells.

This study shows that single nucleosomes encode A/B compartment information through biophysical properties, specifically condensability, which correlates with gene expression and is electrostatic in nature.