Isabelle Anne Leclercq

The paper identifies laminin and liver sinusoidal endothelial cells as key regulators of cholangiocyte fate in chronic liver disease, showing that preventing LSEC capillarization enhances DR differentiation into hepatocytes.

This study investigates how MASH impairs endothelial function via NO-dependent mechanisms and identifies ADMA as a key liver-derived mediator.

This study examines cardiac remodelling in MASH mouse models, finding adverse structural changes in the heart linked to liver disease, not overfeeding or aging.

The study shows that combining G-CSF and HNF4 overexpression rescues vascular damage and improves survival after extended hepatectomy in mice.