Ting Zhang

This study identifies metabolic differences between regions and tissues in the human retina and RPE/choroid using targeted metabolomics.

The paper identifies differences in stress response and function between macular and peripheral Muller cells, linking these differences to vulnerability to degenerative diseases.

This study shows TDP-43 mutations disrupt miRNA biogenesis by affecting Dicer activity, leading to cytotoxicity in Drosophila and in vitro models.

This study evaluates the drug developability of LG157, a MKLP2 inhibitor, by assessing its pharmacokinetics, tissue distribution, and formulation using SEDDS.

This study shows that LXY18 selectively kills MYC-overexpressing cancer cells by inducing mitotic arrest, offering a new approach to target MYC-driven tumors.

The paper identifies metabolic differences between mouse and human retinas, cones vs. rods, macula vs. periphery, and retina vs. RPE, highlighting distinct metabolic pathways and nutrient exchange.

The paper generates a human neural retina transcriptome atlas using single-cell RNA sequencing, identifying 18 cell types and revealing a novel role for MALAT1 in rod degeneration.