Guohua Yi

This study characterizes a bacteriophage, Curly, against Klebsiella pneumoniae, showing its efficacy in reducing bacterial burden and inflammation in human cells and a mouse model.

This study shows that Sirt2 inhibition reduces HIV-1 and Mtb replication in macrophages and humanized mice, suggesting a dual therapeutic strategy.

This study uses spatial transcriptomics to analyze HIV and tuberculosis coinfection in humanized mice, revealing distinct immune cell infiltration patterns and transcriptional signatures in early infection stages.

This study develops a humanized mouse model to study HIV and tuberculosis co-infection, showing it recapitulates human immune, pathological, and metabolic responses.