Gundeep Singh

The paper investigates how DNA braiding geometry affects supercoiling partitioning during replication, showing that substrate geometry influences torsional resistance and fork rotation.

This study investigates the torsional mechanics of circular DNA, showing that underwound DNA has a torque near the melting threshold and equal force/torque distribution, with implications for DNA-protein interactions.

This study shows that chromatin enhances topoisomerase II processivity under both high and low torsional stress, with topo II relaxing over 6000 DNA turns on plectonemic DNA.