Meiling Wu

This study investigates how Rad51 and Rad54 remodel donor DNA during homology search by applying tension and torsion forces, revealing their role in controlling Rad51-ssDNA filament dynamics.

This study identifies a new role for human topoisomerase IIα in promoting chromatin condensation through a polymer-collapse phase transition, independent of its catalytic activity.

This study shows that chromatin enhances topoisomerase II processivity under both high and low torsional stress, with topo II relaxing over 6000 DNA turns on plectonemic DNA.