Yasushi Kawaguchi

This study identifies calmodulin as a host factor that accelerates HSV-1 gene-expression tempo, increasing virus-producing cells and protecting mice from lethal infection.

This paper identifies HSV-2 UL55 and Us10 as viral activators of the UL13 protein kinase, showing UL55 is a principal activator and Us10 is an auxiliary activator for kinase activity and viral replication.

This study identifies herpesvirus protein kinases that mimic CDK regulation, showing their role in viral replication and pathogenicity.

This study shows that expressing human APP in endothelial cells of mice leads to cerebral amyloid angiopathy, highlighting the role of both neuronal and endothelial APP in vascular Aβ deposition.