Zacharias Papadovasilakis

This study identifies an immunosuppressive mechanism in the tumor microenvironment where SMA+ cancer-associated fibroblasts process and present tumor antigens via autophagy to form immunological synapses with Foxp3+ T regulatory cells, promoting tumor development.

This study compares three feature selection algorithms for gene expression data, finding that gOMP outperforms LASSO and matches FBED in performance while being more computationally efficient.