Felix Mueller‐Planitz

The paper identifies DDK-mediated phosphorylation of INO80's Arp8 subunit, which stabilizes the complex and regulates nucleosome spacing at replication origins, enhancing replication efficiency and stress response.

The paper shows that the Ies6 subunit is essential for INO80-mediated nucleosome organization in yeast, with its deletion disrupting nucleosome spacing and array regularity.

This study examines how H3K36me3 and H4K5/8/12/16ac histone modifications affect nucleosome structure and interactions in tri-nucleosome arrays, revealing distinct mechanisms for inducing open conformations.

This study shows ISWI catalyzes nucleosome sliding in condensed chromatin and requires ATP hydrolysis for mobility, with simulations supporting a monkey-bar mechanism.

This study investigates the biogenesis and function of nucleosome arrays in yeast, showing that transcription and chromatin remodeling complexes like INO80 shape nucleosome positioning and protect the genome.