Author

Nicola Hepp

Copenhagen University HospitalORCID 0000-0003-4571-0439Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1 Organism:Drosophila· 1

Frequent Co-Authors

Felix Mueller‐PlanitziD· 2 shared Alessandro ScacchettiiD· 1 shared Dieter KampiD· 1 shared Evdoxia Karagianni· 1 shared Jan LipfertiD· 1 shared Johannes StigleriD· 1 shared Joseph D. BarthoiD· 1 shared Mariano Gonzalez PisfiliD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Felix Mueller‐PlanitzORCID

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2 papers

Recent·Most cited

BiophysicsJournal of Molecular BiologyPeer-reviewedJun 20, 2024

Epigenetic histone modifications H3K36me3 and H4K5/8/12/16ac induce open polynucleosome conformations via different mechanisms

Yi-Yun Lin, Peter K Müller, Evdoxia Karagianni…·Jan Lipfert

This study examines how H3K36me3 and H4K5/8/12/16ac histone modifications affect nucleosome structure and interactions in tri-nucleosome arrays, revealing distinct mechanisms for inducing open conformations.

16 citations

experimental assaychromatin & epigenetic regulation

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BiochemistryNature Structural & Molecular BiologyPeer-reviewedApr 25, 2024

ISWI catalyzes nucleosome sliding in condensed nucleosome arrays

Petra Vizjak, Dieter Kamp, Nicola Hepp…·Felix Mueller‐Planitz

This study shows ISWI catalyzes nucleosome sliding in condensed chromatin and requires ATP hydrolysis for mobility, with simulations supporting a monkey-bar mechanism.

15 citations

DrosophilaChIP-seq

𝕏 PostBluesky