Author
University of Massachusetts Chan Medical SchoolORCID 0000-0001-8409-235XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Sukanya Iyer, Katelyn Daman, Yehui Sun…·Scot A. Wolfe
SORT LNPs enable efficient Cas9-mediated repair of a pathogenic allele in skeletal muscle in a mouse model of LGMDR7.
Terence R. Flotte, Meghan Blackwood, Motahareh Arjomandnejad…·Allison M. Keeler
This study characterizes immune responses to AAVrh8 gene therapy in CNS patients and evaluates the effectiveness of immunosuppression.
Pengpeng Liu, Karthikeyan Ponnienselvan, Thomas Nyalile…·Scot A. Wolfe
This study identifies mutations to improve prime editing efficiency in low-dNTP environments by enhancing MMLV-reverse transcriptase and reducing SAMHD1 activity.
Sukanya Iyer, Aamir Mir, Joel Vega‐Badillo…·Scot A. Wolfe
This paper demonstrates that circular ssDNA donors improve HDR efficiency and reduce off-target integration compared to linear ssDNA donors in mammalian cells.