Author

Yousef M. O. Alhammad

University of KansasORCID 0000-0001-8435-9042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anthony R. FehriD· 2 shared Anuradha RoyiD· 2 shared Joseph J. O’Connor· 2 shared Philip Gao· 2 shared Reem Khattabi· 2 shared Catherine Kerr· 1 shared Catherine M. KerriD· 1 shared David K. JohnsoniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

Anthony R. FehrORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedJul 30, 2025

Mutations differentially affecting the coronavirus Mac1 ADP-ribose binding and hydrolysis activities indicate that it promotes multiple stages of the viral replication cycle

Joseph J. O’Connor, Anuradha Roy, Reem Khattabi…·Anthony R. Fehr

This paper investigates how mutations in the coronavirus Mac1 protein affect ADP-ribose binding and hydrolysis, revealing distinct roles in viral replication stages.

3 citations

mouseexperimental assay

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MicrobiologyJournal of VirologyPeer-reviewedOct 10, 2024

Mutation of a highly conserved isoleucine residue in loop 2 of several ????-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental to infection

Catherine M. Kerr, Jessica J. Pfannenstiel, Yousef M. O. Alhammad…·Anthony R. Fehr

This study shows that mutating a conserved isoleucine in the macrodomain of MERS-CoV and SARS-CoV-2 enhances ADP-ribose binding but reduces viral replication and pathogenesis.

19 citationstop 3%

mousehuman

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