Nicolas B. Strauli

This study uses single-cell RNA sequencing to analyze immune changes after B-cell depletion in MS patients, revealing cell type-specific effects on macrophages, monocytes, and T cells.

This study shows Ebola virus can infect boa constrictor cells without causing cytopathic effect or requiring genomic adaptation, while Marburg virus cannot.

This paper introduces ROP to identify the source of unmapped RNA-Seq reads across diverse tissues, showing it can account for 99.9% of 1 trillion reads and reveals immune and microbial correlations.

The paper analyzes amino acid mutation patterns across 29 cancers, identifying six mutation signatures, five of which are validated using COSMIC data.