Xiqun Chen

This study shows that Parkin is essential for neuronal differentiation and survival, and small molecule Parkin agonists like FB231 protect dopaminergic neurons in Parkinson's disease models.

This study identifies immune factor profiles in blood and CSF associated with LRRK2 mutations and Parkinson's disease, showing distinct changes in serum and CSF markers.

AutoMorphoTrack automates organelle morphology, motility, and interaction analysis from fluorescence microscopy images, providing reproducible, publication-ready outputs.

The paper shows that low-dose carbon monoxide reduces Parkinson's disease pathology in rodent models by activating HO-1, similar to the protective effect observed in smokers.

This study shows that the LRRK2 G2019S mutation impairs Th9 and Treg cell differentiation while enhancing Th2 differentiation through JAK/STAT3 signaling in T cells.

This study shows that FASlpr gene dosage affects lymphoproliferation and T cell differentiation in lupus models, with heterozygous Faslpr leading to increased autoantibodies and Th1 cell skewing.