Peng Zhou

This paper develops a conditional plasmid system for gene deletion in non-model Fusobacterium nucleatum strains, successfully generating mutants in multiple subspecies and related species.

This paper develops a SacB-based counterselection method for efficient allelic exchange in Fusobacterium nucleatum, enabling unmarked gene mutations without requiring a modified host.

This study identifies a bacterial P-type ATPase transporter, PtaT, that specifically binds and mediates the uptake of host-derived tsRNAs in Fusobacterium nucleatum.

This paper introduces a CRISPRi system for efficient gene inactivation in Fusobacterium nucleatum, demonstrating its effectiveness in both model and resistant strains.