Author

Erik Michaëlsson

AstraZeneca (Sweden)ORCID 0000-0001-8643-2821Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Anita SalamoniD· 1 shared Anna Tochwin· 1 shared Anna WalentinssoniD· 1 shared Bengt Kull· 1 shared Charles R. TyleriD· 1 shared Gabriel F. AlencariD· 1 shared Gary K. OwensiD· 1 shared Heather DoviakiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

Anita SalamonORCID

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2 papers

Recent·Most cited

PhysiologyCirculationPeer-reviewedJun 17, 2024

Mouse Model of Heart Attack and Stroke Shows Improved Survival with MPO Inhibition

Sohel Shamsuzzaman, Rebecca A. Deaton, Anita Salamon…·Gary K. Owens

The paper introduces a mouse model of advanced atherosclerosis that exhibits spontaneous plaque rupture leading to MI or stroke, and shows that MPO inhibition with AZM198 reduces mortality and plaque rupture incidence.

62 citationstop 1%

mouseexperimental assay

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Molecular BiologyFrontiers in PharmacologyPeer-reviewedApr 25, 2022

A combined human in silico and CRISPR/Cas9-mediated in vivo zebrafish based approach for supporting gene target validation in early drug discovery

Matthew J. Winter, Yosuke Ono, Jonathan S. Ball…·Mohammad Bohlooly‐Y

The paper identifies three genes associated with heart failure using human exome sequencing and validates their roles in cardiovascular function using zebrafish CRISPR/Cas9 mutagenesis.

11 citations

zebrafishwhole-exome sequencing

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