Author

Sophie Wiszniak

South Australia PathologyORCID 0000-0001-8666-9300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Quenten SchwarziD· 3 shared Deepti DomingoiD· 2 shared Jasmine Hartmann· 2 shared Markus Tondl· 2 shared Ceilidh L. MarchantiD· 1 shared Chaya KalcheimiD· 1 shared Congenital Heart Disease Synergy Group· 1 shared David Scott WinlawiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersDevelopmental Biology

Quenten SchwarzORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintNov 11, 2026

Hyaluronic acid dynamics are regulated by neural crest cells and NEDD4 in the developing cardiac outflow tract valves

Jasmine Hartmann, Deepti Domingo, Sarah Boyle…·Sophie Wiszniak

This study shows that NEDD4 in neural crest cells regulates HA synthesis in cardiac outflow tract valves, affecting valve development and ECM composition.

DOI 10.64898/2026.11.08.764443

mouseexperimental assay

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Developmental BiologyNature CommunicationsPeer-reviewedJan 22, 2026

Neural crest cell derived DKK1 modulates Wnt signalling in the second heart field to orchestrate cardiac outflow tract development

Sophie Wiszniak, Dimuthu Alankarage, Iman Lohraseb…·Quenten Schwarz

The paper identifies DKK1 from neural crest cells as a regulator of Wnt signaling in the second heart field, crucial for cardiac outflow tract development and linked to congenital heart disease.

4 citationstop 3%

mouseexperimental assay

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Developmental BiologyBMC BiologyPeer-reviewedApr 23, 2021

Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube

Shai Ofek, Sophie Wiszniak, Sarah A. Kagan…·Chaya Kalcheim

The paper uses transcriptome analysis to identify genes involved in Notch-dependent roof plate formation and shows Notch signaling is critical for RP development and fate determination.

12 citations

mousebulk RNA-seq

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