Author

Megan Catherine Schwarz

Tisch Cancer InstituteORCID 0000-0001-8715-2039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ernesto GuccioneiD· 2 shared Federico Di TullioiD· 2 shared Gaetano GargiuloiD· 2 shared Alcida KarziD· 1 shared Alexander Hall HickmaniD· 1 shared Alexander M. TsankoviD· 1 shared Benjamin D. GreenbaumiD· 1 shared Bruno GiottiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Ernesto GuccioneORCID

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2 papers

Recent·Most cited

Cancer BiologyNature GeneticsPeer-reviewedFeb 1, 2025

A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer

Slim Mzoughi, Megan Catherine Schwarz, Xuedi Wang…·Ernesto Guccione

This study identifies an oncofetal cell state that contributes to resistance in colorectal cancer and shows that targeting both this state and LGR5+ CSCs is needed for effective treatment.

97 citationstop 1%

humanbulk RNA-seq

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GenomicseLifePeer-reviewedJun 2, 2021

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain prostate cancer cell fitness

Jessica Ho, Federico Di Tullio, Megan Catherine Schwarz…·Ernesto Guccione

This study identifies HNRNPM as a splicing factor critical for prostate cancer cell growth by regulating splicing fidelity and circRNA biogenesis, suggesting it as a therapeutic target.

57 citationstop 5%

humanbulk RNA-seq

𝕏 PostBluesky