Alcida Karz

This study identifies CNDP1 as a metabolic vulnerability in brain metastasis, showing its inhibition suppresses metastasis and its expression confers metastatic potential.

The paper identifies shared transcriptomic features between melanoma brain metastases and neurodegenerative diseases, highlighting key genes and providing an open-source tool for analysis.

MetFinder uses a deep neural network to automate metastasis burden quantification in histological sections from mouse models, improving throughput and resolution compared to current methods.

This study identifies HNRNPM as a splicing factor critical for prostate cancer cell growth by regulating splicing fidelity and circRNA biogenesis, suggesting it as a therapeutic target.