Holding glycolysis in check though Alox15 activity is required for macrophage M2 commitment and function in tissue repair and anti-helminth immunity.
Dovran Ovezgeldiyev, Vanessa Trefzer, Rory Doolan…·Tiffany Bouchery
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Monash UniversityORCID 0000-0003-2922-0210Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Dovran Ovezgeldiyev, Vanessa Trefzer, Rory Doolan…·Tiffany Bouchery
Lennard Dalit, Chin Wee Tan, Amania A. Sheikh…·Joanna R. Groom
The paper identifies transcriptional modules and cytokine signaling pathways that drive functional heterogeneity in T follicular helper cells across different infections.
Dovran Ovezgeldiyev, Rory Doolan, Vanessa Trefzer…·Tiffany Bouchery
This study screens compounds from the MMV Pathogen Box against a rodent hookworm model to identify anti-blood-feeding agents, finding five compounds effective in vitro and well-tolerated in vivo.
Haozhe Wang, Kristian T. Barry, Aidil Zaini…·Nicola Laraine Harris
This study shows that helminth-induced intestinal hypermotility in mice is driven by smooth muscle changes, not eosinophils or the enteric nervous system.