Matthieu Raoux

This study shows that pancreatic α-cells regulate β-cell network dynamics to maintain nutrient homeostasis, even without metabolic stress.

This study shows that fatty acids from adipocyte lipolysis stimulate insulin secretion via FFAR4 and FFAR1 receptors, highlighting adipose-islet crosstalk in metabolic regulation.

This study develops a microfluidic biosensor using pancreatic islets to monitor glucose levels in vivo, showing strong correlation between islet activity and glucose concentrations.

This study shows that clonal human beta-cell spheroids enhance electrical activity and hormone secretion compared to monolayers, suggesting they are better models for studying beta-cell function.

This paper uses electrophysiological tools to functionally characterize iPSC-derived human β-like cells and assess the impact of a SLC30A8 variant on β-cell electrical coupling.