Louis Delhaye

This study expands a modular cloning platform to enable rapid, customizable construct assembly for MAPPIT assays, demonstrating its application in studying multiple protein-protein interactions.

The paper shows that many reported RNA-chromatin interactions are technical artifacts caused by DNA off-targeting, not true biological interactions.

This study maps the proximity interactome of NR2E3 and its G56R variant using TurboID, revealing interactions with retinal development complexes and identifying BCOR as enriched in the mutant network.

This study identifies SopB-associated host proteins using Virotrap, revealing SopB's interaction with ESCRT-0 and its role in Salmonella's manipulation of host endosomal trafficking.

The paper identifies NESPR, an adrenergic-specific lncRNA, as a regulator of neuroblastoma cell identity that prevents cell death by attenuating stress.

This study shows Dmrta2 represses Pax6 in cortical progenitors and identifies a DNA-binding mutation linked to microcephaly in humans.

The paper introduces a T2A split-link system for proximity labeling proteomics to improve control over enzymatic activity and expression levels, enhancing accuracy in identifying protein interactions.

The paper investigates how different GR ligands affect coregulator recruitment, finding that antagonists and selective modulators reduce interactions with p300/CBP and the Mediator complex compared to full agonists.