Naoki Suzuki

This study identifies LAP3 as a regulator of skeletal muscle mitochondrial homeostasis, showing sex-dependent metabolic consequences in mice.

This study shows zinc finger domains bind low-complexity domain polymers in a cross-β-dependent manner, suppressing polymer formation and preferentially recognizing polymeric LC domains.

The paper shows that three ALS-associated RBPs regulate UNC13A transcription by targeting REST, highlighting their role in synaptic integrity and ALS pathogenesis.

This paper demonstrates a neuron-selective drug delivery system using synaptic vesicle release and recycling mechanism via anti-SYT2 antibodies to deliver therapeutic molecules to motor neurons.

This paper establishes a patient-derived blood-brain barrier model using hiPSCs to study BBB dysfunction in ALS and identifies specific TARDBP mutations that do not cause BBB issues.

This study identifies mitochondrial dysfunction in sporadic inclusion body myositis and shows that MA-5 improves mitochondrial function and protects myoblasts.