Jeffrey S. Bourgeois

This study shows that an Fc-silent variant of the monoclonal antibody LA-2 provides equivalent passive protection against Borrelia burgdorferi in mice, suggesting its protective mechanism is independent of complement.

This study shows CFIm25 enhances macrophage antibacterial immunity against Salmonella by regulating alternative polyadenylation and boosting MAPK and NF-κB signaling.

This study differentiates Peromyscus leucopus bone marrow-derived macrophages and compares their responses to Borrelia burgdorferi and lipopolysaccharide with C57BL/6J macrophages, finding modest transcriptomic differences.

The paper compares transcriptomic responses to larval Ixodes scapularis bites in Peromyscus leucopus, Mus musculus, and humans, finding distinct immune activation patterns.

This study compares the ability of three rodent species to support Borrelia burgdorferi infection and transmission, finding higher bacterial burdens in laboratory mice and reduced transmission from white-footed deermice.

The paper identifies genetic variation in MCOLN2 that limits Salmonella Typhi replication via magnesium deprivation in human cells.

The paper identifies a nonsynonymous ERAP1 variant associated with increased susceptibility to influenza virus using scHi-HOST, a single-cell method for genetic susceptibility testing.