Author

Dagmara McGuinness

University of GlasgowORCID 0000-0001-9057-3504Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Carla JohnsoniD· 2 shared Christopher A. MoxoniD· 2 shared Abel Tembo· 1 shared Andrew J. RoeiD· 1 shared Andrew J. SmithiD· 1 shared Ben MortoniD· 1 shared Benjamin KumwendaiD· 1 shared Charalampos AttipaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Carla JohnsonORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJul 16, 2026

Bacterial histone-like proteins released during antibiotic treatment mediate vascular injury in meningococcal sepsis.

Dagmara McGuinness, Carla Johnson, Leandro Lemgruber…·Christopher A. Moxon

Antibiotic treatment of meningococcal and other sepsis causative bacteria triggers the release of histone-like proteins (HLPs) that damage the endothelium and drive coagulopathy, but these effects can be neutralized by non-anticoagulant heparins or anti-HLP antibodies.

DOI 10.64898/2026.07.15.738198

humanproteomics

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ImmunologyNature MedicinePeer-reviewedNov 20, 2024

Spatially resolved single-cell atlas of the lung in fatal Covid19 in an African population reveals a distinct cellular signature and an interferon gamma dominated response

James Nyirenda, Olympia M Hardy, João Luiz Silva‐Filho…·Christopher A. Moxon

The paper presents a spatially resolved single-cell atlas of lung tissue from fatal Covid19 cases in an African population, revealing a distinct cellular signature and an interferon gamma-dominated response.

9 citations

humanscRNA-seq

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