Author

Jessica D. S. Grassmann

The Jackson Laboratory for Genomic MedicineORCID 0000-0001-9076-452XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Diane Luo· 2 shared Elise T. CourtoisiD· 2 shared William F. FlynniD· 2 shared Aaron Michael TayloriD· 1 shared Adam D. LindsayiD· 1 shared Alini Trujillo-PaolilloiD· 1 shared Alissa M. DzisiD· 1 shared Andrew E. GoodspeediD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Diane Luo

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2 papers

Recent·Most cited

Cancer BiologyCancersPeer-reviewedJun 24, 2025

Immunosuppressive tumor microenvironment of osteosarcoma

Aaron Michael Taylor, Jianting Sheng, Patrick Kwok Shing Ng…·Ching C. Lau

This study identifies immunosuppressive mechanisms in osteosarcoma using single-cell and spatial transcriptomics, revealing interactions between MDSCs, T-cells, and tumor cells that promote an immunosuppressive microenvironment.

39 citationstop 1%

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologyCell ReportsPeer-reviewedMay 1, 2025

Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response in mice and humans

Daniel A. Skelly, John P. Graham, Mingshan Cheng…·Edison T. Liu

The paper identifies host genetic factors influencing anti-PD-1 response in mice and humans by mapping QTLs and finding a core gene network with prognostic value in human tumors.

5 citations

mousehuman

𝕏 PostBluesky