Jennifer S Lin

This study investigates how LL-37 binds to nucleic acids, forming complexes that affect DNA structure and NET clearance, with implications for immune regulation and disease.

The paper develops a peptide-based therapy that targets intracellular Pseudomonas aeruginosa and synergizes with obsolete antibiotics to reduce bacterial reservoirs.

This study demonstrates that the peptide-mimetic TM5 effectively kills Pseudomonas aeruginosa in vitro and reduces bacterial load in a mouse model of infection with low toxicity.

This study shows HIPK4 is essential for spermiogenesis and male fertility in mice, with defects in sperm head morphology and fertility.