Author
Babraham InstituteORCID 0000-0001-9185-4922Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Todd Watts, Harvey E. Johnston, Yasmeen Al-Mufti…·Rahul S. Samant
This study shows that senescent human cells secrete misfolded proteins via the endo-lysosomal system, driven by DNAJC5 and reduced intracellular proteostasis.
M. Teresa Bertran, Robert Walmsley, T. F. M. Cummings…·Louise J. Walport
The paper develops cyclic peptide modulators of PADI4 and reveals their mechanism of action and cellular activity.
Katsiaryna Maskalenka, Gökberk Alagöz, Felix Krueger…·Peter J. Rugg‐Gunn
The paper shows NANOGP1, a duplicate of NANOG, has partial functional conservation in human naive pluripotent stem cells, contributing to pluripotency but not maintaining undifferentiated status.
Clara Lopes Novo, Emily V. Wong, Colin Hockings…·Peter J. Rugg‐Gunn
This study shows that satellite repeat transcripts in mouse ESCs drive heterochromatin condensates, which are crucial for chromosome stability and nuclear organization.
Piero Dalle Pezze, Eleftherios Karanasios, Varvara Kandia…·Nicholas T. Ktistakis
This study uses live imaging and mathematical modeling to analyze ATG13 dynamics in non-selective autophagy and mitophagy, revealing distinct patterns of translocation and their relationship to mitochondrial fragment size.