Author
The Francis Crick InstituteORCID 0000-0002-8336-0903Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Hugo Belda, David Bradley, Evangelos Christodoulou…·Moritz Treeck
This study investigates the evolution and inhibition of FIKK kinases in P. falciparum, showing they can be inhibited by a single compound.
Jack P. C. Williams, Tania Auchynnikava, Afshan McCarthy…·Louise J. Walport
The paper investigates PADI6's role in oocyte cytoplasmic lattices using single-cell proteomics and transcriptomics, revealing its critical scaffolding function and connections to other oocyte compartments.
M. Teresa Bertran, Robert Walmsley, T. F. M. Cummings…·Louise J. Walport
The paper develops cyclic peptide modulators of PADI4 and reveals their mechanism of action and cellular activity.
Jack P. C. Williams, Stéphane Mouilleron, Rolando Hernández Trapero…·Louise J. Walport
This study determines the crystal structure of human PADI6, revealing structural differences that suggest it lacks catalytic activity compared to other PADIs.