Valeria Manara

This study shows that glutaminase (GLS) mediates Myc-induced autophagy in Drosophila wing discs and links Myc-dependent glutamine metabolism to non-autonomous autophagy in RasV12-transformed epithelia.

The paper shows that Noc1 downregulation in Drosophila causes nucleolar stress, increases p53 levels, and specifically upregulates the truncated p53E isoform, which may modulate apoptosis.

This study identifies CEBPZ, NOC2L, and NOC3L as conserved regulators of rRNA processing and tumor growth, showing context-dependent expression patterns in cancers.

This study identifies NOC1 as a direct MYC target and shows its role in nucleolar function through protein interactions and structural changes.