Author

Isabel Soria‐Bretones

University Health NetworkORCID 0000-0001-9309-754XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Alejandro Álvarez-QuilóniD· 1 shared Andrew EliaiD· 1 shared Ariya Shiwram· 1 shared Artur VelosoiD· 1 shared Benson Z. Wu· 1 shared C. Gary MarshalliD· 1 shared Caterina Di Ciano‐Oliveira· 1 shared Cathy Caron· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alejandro Álvarez-QuilónORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 15, 2025

A dual mechanism of sensitivity to PLK4 inhibition by RP-1664 in neuroblastoma

Isabel Soria‐Bretones, Matias Casás‐Selves, Elliot Goodfellow…·Michal Zimmermann

This study shows neuroblastoma cells are hypersensitive to PLK4 inhibitor RP-1664 due to dual mechanisms of centriole loss and amplification, leading to cell death.

5 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyCancer Gene TherapyPeer-reviewedAug 23, 2024

Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification

Christopher Zhang, Benson Z. Wu, Caterina Di Ciano‐Oliveira…·Kelsie L. Thu

This study identifies KIFC1 as a therapeutic vulnerability in lung cancers with centrosome amplification by showing its role in mitigating mitotic stress.

21 citations

humanbulk RNA-seq

𝕏 PostBluesky