Author

Rekha C. Patel

University of South CarolinaORCID 0000-0001-9434-4880Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Samuel B. Burnett· 2 shared Taylor Rowson· 2 shared Allison M. Culver· 1 shared Allison Reed· 1 shared Emily G. McIntyre· 1 shared Jeffry L. DudychaiD· 1 shared Julianna C. Aiello· 1 shared Kenneth Frederick· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenetics

Samuel B. Burnett

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 12, 2026

PKR inhibition prevents maladaptive responses to endoplasmic reticulum (ER) stress in early-onset dystonia DYT-PRKRA.

Emily G. McIntyre, Sravanthi Avula, Taylor Rowson…·Rekha C. Patel

This study shows PKR inhibition reduces apoptosis in DYT-PRKRA cells by blocking CHOP induction, suggesting it as a potential therapy for this dystonia.

DOI 10.64898/2026.11.09.765397

humanexperimental assay

𝕏 PostBluesky

GeneticsbioRxivPreprintOct 2, 2025

Genetic background influences the effects of RNAi-by-feeding for DNA methyltransferases in Daphnia pulex.

Trenton C. Agrelius, Krista B. Harmon, Allison Reed…·Jeffry L. Dudycha

The paper investigates how genetic background affects RNAi-induced changes in DNA methyltransferase expression in Daphnia pulex, finding significant genotypic differences and cross-reactivity in gene silencing.

DOI 10.1101/2025.10.02.680119

DrosophilaDNA methylation

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Molecular BiologybioRxivPreprintJun 4, 2024

A frameshift mutation in the murine Prkra gene causes dystonia and exhibits abnormal cerebellar development and reduced eIF2α phosphorylation.

Samuel B. Burnett, Allison M. Culver, Tricia A. Simon…·Rekha C. Patel

This study investigates the effects of a Prkra frameshift mutation in mice, showing reduced eIF2 phosphorylation and cerebellar abnormalities linked to dystonia.

2 citations

mousestatistical model

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