Author

Zhiping Ruan

Harvard UniversityORCID 0000-0001-9467-7466Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Dan Gabriel DudaiD· 2 shared Tatsuya KobayashiiD· 2 shared Adegboyega K. OyelereiD· 1 shared Alexei HernandeziD· 1 shared Alexis JohnstoniD· 1 shared Atsuyo MoritaiD· 1 shared Aya MatsuiiD· 1 shared Bocheng WuiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Dan Gabriel DudaORCID

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2 papers

Recent·Most cited

Cancer BiologyACS Pharmacology & Translational SciencePeer-reviewedSep 5, 2024

A Novel Liver Cancer-Selective Histone Deacetylase Inhibitor Is Effective Against Hepatocellular Carcinoma and Induces Durable Responses with Immunotherapy

Bocheng Wu, Subhasish Tapadar, Zhiping Ruan…·Adegboyega K. Oyelere

This paper identifies a novel HDAC inhibitor, STR-V-53, that effectively targets HCC and enhances immunotherapy responses in mouse models.

8 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 20, 2023

Liver fibrosis uncouples tumor control from survival after multikinase inhibitor immunotherapy in hepatocellular carcinoma

Satoru Morita, Tomofumi Ando, Hiroto Kikuchi…·Dan Gabriel Duda

Liver fibrosis limits the survival benefit of multikinase inhibitor immunotherapy in hepatocellular carcinoma by promoting innate immune-mediated hepatotoxicity despite preserved tumor control.

3 citations

𝕏 PostBluesky