Abeer Dannoura

This study identifies biallelic UQCC1 variants as a cause of early-onset mitochondrial disease by impairing complex III assembly and function.

This study uses proteomic analysis to reveal reprogramming in macrophages during efferocytosis, showing an alternatively activated phenotype and secretome-driven reprogramming of naive macrophages.

The paper develops a flow cytometry-based method combined with ultra-sensitive proteomics to study host-pathogen interactions in Salmonella-infected macrophages, revealing new insights into virulence factor induction and phagosomal dynamics.

The paper compares proteomic profiles of murine macrophage cell lines to primary and immortalised bone marrow-derived macrophages, identifying J774A.1 as the most similar to primary cells.

This paper uses proteomics to show trilaciclib induces senescence in CML and NSCLC cells by stabilizing CDK4/6 and activating autophagy.