Frederic Woodward Hopf

The paper classifies mice into high and low engaged groups based on their performance in the 5-Choice Serial Reaction Time Task with alcohol as a reward, finding that low-engaged mice show increased responding after intermittent alcohol access.

This study investigates the role of alpha- and beta-adrenergic receptors in compulsion-like alcohol drinking using rat models and finds that propranolol reduces alcohol intake through mechanisms not limited to specific brain regions.

This study examines how alcohol preference and consumption affect task engagement in mice during a waiting task for alcohol, finding that preference better predicts performance than consumption and that chronic alcohol exposure enhances engagement, especially in low-preference mice.

The paper identifies specific firing patterns in anterior insular cortex neurons that correlate with compulsion-like alcohol consumption in rats.

This study examines sex differences in alcohol drinking strategies in rats, finding females show greater persistence under lower challenge but different patterns under higher challenge.

The paper generates and validates two knock-in rat strains expressing Cre or Flp recombinase under the Parvalbumin promoter for studying inhibitory interneurons.