Hitoshi Sawa

The paper shows that Wnt proteins, receptors, and Dvl localize asymmetrically in C. elegans seam cells, linking Wnt gradients to cell polarity through positive feedback.

The paper investigates the distinct and cooperative roles of multiple Wnt ligands and receptors in regulating cell polarity orientation in C. elegans.

The paper shows that three Wnt proteins control the polarity of somatic gonadal precursors in C. elegans, which is essential for mirror-symmetric gonad development.