Stefano Pagliara

This study investigates how Burkholderia thailandensis responds to antibiotics and phages in spatial refuges, revealing distinct subpopulation behaviors and interactions.

This study shows that loss of type I restriction-modification methyltransferases in Pseudomonas aeruginosa increases fluoroquinolone persistence through enhanced SOS response and slower growth.

This study identifies 52 genes in MRSA associated with reduced vancomycin survival, emphasizing the role of prophage loci, metabolism, and stress responses over discrete resistance mechanisms.

This paper introduces a geometric model to predict microbial growth across environments, achieving higher accuracy than existing models.

This paper introduces a parallelised microscope array to rapidly assess bacterial viability via fluorescence response to electrical stimuli, achieving results in under a minute.

This paper introduces a millifluidic device with agar sheets to enable spatially structured microbial growth, demonstrating extended growth and spatial control compared to traditional agar plates.

This study investigates how Yersinia pseudotuberculosis survives antimicrobials using persisters, the Eagle effect, tolerance, and enzyme overexpression.

The paper shows hybrid membranes select for D-ribose, deoxyribose, and specific L-amino acids, suggesting membrane permeability influenced life's stereochemistry.

This study shows that S. aureus enters a viable but non-culturable state when competing with P. aeruginosa, altering its metabolism and survival strategies in response to antibiotics.

This study uses nanomotion technology to rapidly test Salmonella enterica's susceptibility to azithromycin, showing correlation with traditional susceptibility measures.

This study shows that antibiotic-resistant bacteria survive treatment by doubling while shrinking, revealing distinct resistance mechanisms in different environments.

This study shows that subpopulations of stationary phase bacteria resist antimicrobial peptides through enhanced efflux and other mechanisms, and suggests combining tachyplesin with sertraline to combat resistance.

This study shows that phage presence reduces antibiotic efflux in bacteria, enhancing antibiotic efficacy and enabling lower concentrations for treatment.