Shuang Chen

This paper introduces a method for self-extending DNA recording that combines stochastic and programmed writing, enabling the accumulation of cellular histories with joint cellular and tissue readout.

This paper identifies WWP2 as a regulator of myofibroblast metabolic reprogramming in renal fibrosis, showing it suppresses PGC-1 to alter metabolic pathways and reduce fibrosis severity.

The paper identifies NAT10's role in cancer through tRNA ac4C modification, showing RNPS1 stabilizes NAT10 and enhances translation efficiency via the AP-1 pathway.

This paper identifies a cuproptosis-related lncRNA signature that predicts prognosis in hepatocellular carcinoma and shows its association with survival and immune responses.