Margaret A. Strong

The paper introduces an optimized AID system for reversible and sustained protein degradation in live mice, demonstrating its effectiveness in degrading CEP192 and causing cell division failure.

This study shows that HYLS1 mutations cause centriole structural defects leading to ciliary dysfunction and developmental issues in mice, mirroring human Hydrolethalus Syndrome.

This study identifies a new TIN2 isoform, TIN2M, and shows that all TIN2 isoforms enhance telomerase processivity beyond TPP1/POT1, suggesting TIN2 is a functional component of the TPP1/POT1 complex.

This study evaluates the diagnostic and prognostic value of telomere length measurement in a hospital setting, finding it alters treatment decisions in a subset of bone marrow failure patients.

This study identifies BRD4 as a telomere length regulator and shows that BRD4 inhibitors block telomere elongation in mouse and human cells.