Francie Moehring

This study identifies Piezo1 as the major mechanotransducer in keratinocytes for detecting mechanical stimuli and transmitting tactile information to sensory neurons.

The paper identifies Piezo2 expression in neuronal and non-neuronal cells of the rat peripheral sensory pathway and links its elevation to pain conditions.

This study identifies TRPC5 as a mediator of inflammatory mechanical pain using knockout mice and pharmacological inhibitors, showing its role in pain behaviors induced by lysophosphatidylcholine.

This study shows keratinocytes are essential for normal cold and heat sensation in mammals through calcium release and ATP-P2X4 signaling.