Klemen Strle

This study develops a durable Lyme disease vaccine using CspZ-YAC187S antigen with Alum-CpG and Alum-Gal adjuvants, showing long-term protective immunity and memory responses.

This study uses long-read assemblies to show that genetic modules across multiple plasmids organize Borrelia burgdorferi strain variation and influence virulence in Lyme disease.

This paper shows that HLA-DR-expressing fibroblast-like synoviocytes can present Lyme autoantigens and activate CD4+ T cells when stimulated with IFN-gamma and Borrelia burgdorferi.