Author

Andrew R Mack

United States Department of Veterans AffairsORCID 0000-0002-0131-7996Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Alexander L. GreningeriD· 1 shared Andrea M. HujeriD· 1 shared Christopher R. BetheliD· 1 shared Gregory PEPPER· 1 shared Jared Castor· 1 shared Katharine H. D. CrawfordiD· 1 shared Katrina LaTurner· 1 shared Robert A. BonomoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

Alexander L. GreningerORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 27, 2026

Six years of clinical herpes simplex virus genotypic acyclovir resistance testing confirms common resistance mechanisms and identifies novel mutations

Katharine H. D. Crawford, Jared Castor, Katrina LaTurner…·Alexander L. Greninger

This paper reviews six years of clinical HSV acyclovir resistance testing, confirming common resistance mechanisms and identifying 23 novel UL23 mutations.

DOI 10.64898/2026.06.25.734554

humanDNA methylation

𝕏 PostBluesky

BiophysicseLifePeer-reviewedJan 21, 2026

{Omega}-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

Shuang Chen, Andrew R Mack, Andrea M. Hujer…·Shozeb M Haider

This study investigates how {Omega}-loop mutations in PDC-3 β-lactamase affect its active site dynamics and catalytic activity through molecular simulations.

10 citationstop 5%

bacteria (other)structural biology

𝕏 PostBluesky