Cancer BiologyScientific ReportsPeer-reviewed
Matched three-dimensional organoids and two-dimensional cell lines of melanoma brain metastases mirror response to targeted molecular therapy
William Harrison Hicks, Lauren C. Gattie, Mohamad El Shami…·Kalil G. Abdullah
This study develops matched patient-derived organoids and cell lines from melanoma brain metastases to evaluate responses to targeted therapies, finding both models respond to BRAF and MEK inhibitors.
9 citations