Author

Lauren C. Gattie

University of PittsburghORCID 0009-0002-9437-0610Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Kalil G. AbdullahiD· 3 shared Mohamad El ShamiiD· 3 shared Samuel K. McBrayeriD· 3 shared Timothy E. RichardsoniD· 3 shared William Harrison HicksiD· 3 shared Jeffrey Isaac TrayloriD· 2 shared Kimmo J. HatanpaaiD· 2 shared Michael M. LevittiD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Kalil G. AbdullahORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyCellPeer-reviewedSep 1, 2026

Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth

Kalil G. Abdullah, Kenji Miki, Charles K. Edgar…·Samuel K. McBrayer

This study identifies GAA accumulation in gliomas as a driver of neuronal activity and tumor growth, linking cancer metabolism to neuroscience through GABAA receptor activation.

1 citationtop 4%

humanmetabolomics

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Cancer BiologyScientific ReportsPeer-reviewedOct 22, 2024

Matched three-dimensional organoids and two-dimensional cell lines of melanoma brain metastases mirror response to targeted molecular therapy

William Harrison Hicks, Lauren C. Gattie, Mohamad El Shami…·Kalil G. Abdullah

This study develops matched patient-derived organoids and cell lines from melanoma brain metastases to evaluate responses to targeted therapies, finding both models respond to BRAF and MEK inhibitors.

9 citations

humanexperimental assay

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BioinformaticsCancer InformaticsPeer-reviewedJan 1, 2022

Semi-automated computational assessment of cancer organoid viability using rapid live-cell microscopy

Joseph Buehler, Cylaina E. Bird, Milan R. Savani…·Kalil G. Abdullah

This paper develops a method to assess cancer organoid viability using rapid imaging and a fragmentation algorithm, finding significant correlations between SSD scores and traditional viability markers.

3 citations

humanimaging

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