Yue Chen

This study reveals how the BRCA2 C-terminal domain reshapes RAD51 dimers to bind B-DNA, promoting replication fork stability over homology-directed repair.

This study shows sorbate induces lysine sorbylation via Class I HDACs, altering inflammation gene expression without affecting histone acetylation.

This study identifies PHD2 interaction hotspots and reveals its role in regulating protein neddylation through interaction with the COP9 Signalosome complex.

This study finds that neutrophil extracellular traps (NETs) formation is linked to postoperative complications in neonates and infants after congenital cardiac surgery.

The paper introduces a computational tool to analyze ubiquitin E3 ligase activity using quantitative proteomics data and validates it with experimental results.