Author

Robert S. Sabatini

University of GeorgiaORCID 0000-0002-0188-0201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Haidong YaniD· 2 shared Robert J. SchmitziD· 2 shared Rudo KieftiD· 2 shared Laura J. Cliffe· 1 shared Stephen L. Hajduk· 1 shared Yang ZhangiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Haidong YanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 21, 2024

Mono-allelic epigenetic regulation of bi-directional silencing of RNA Polymerase II polycistronic transcription initiation in Trypanosoma brucei.

Rudo Kieft, Laura J. Cliffe, Haidong Yan…·Robert S. Sabatini

The paper shows that epigenetic mechanisms, including base J modification, regulate mono-allelic transcriptional silencing of adjacent polycistronic gene clusters in Trypanosoma brucei.

DOI 10.1101/2024.06.21.600114

bulk RNA-seqChIP-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 21, 2023

Protein Phosphatase PP1 Regulation of Pol II Phosphorylation is Linked to Transcription Termination and Allelic Exclusion of VSG Genes and TERRA in Trypanosomes.

Rudo Kieft, Yang Zhang, Haidong Yan…·Robert S. Sabatini

This study shows that PP1-1 modulates Pol II termination in T. brucei by dephosphorylating the Pol II large subunit, leading to readthrough transcription and pervasive genome transcription.

3 citations

experimental assay

𝕏 PostBluesky