Author

Yang Zhang

University of GeorgiaORCID 0000-0001-7462-2935Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yang Zhang10 papers · St. Jude Children's Research Hospital

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Robert S. SabatiniiD· 2 shared Haidong YaniD· 1 shared Robert J. SchmitziD· 1 shared Rudo KieftiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

Robert S. SabatiniORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedNov 3, 2023

Leishmania PNUTS discriminates between PP1 catalytic subunits through a RVxF-{Phi}{Phi}-F motif and polymorphisms in the PP1 C-tail and catalytic domain

Yang Zhang, Robert S. Sabatini

This paper identifies how PNUTS interacts with PP1-8e through specific motifs and polymorphisms to form the PJW/PP1 complex, regulating Pol II transcription in Leishmania.

3 citations

proteomicsexperimental assay

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Molecular BiologybioRxivPreprintOct 21, 2023

Protein Phosphatase PP1 Regulation of Pol II Phosphorylation is Linked to Transcription Termination and Allelic Exclusion of VSG Genes and TERRA in Trypanosomes.

Rudo Kieft, Yang Zhang, Haidong Yan…·Robert S. Sabatini

This study shows that PP1-1 modulates Pol II termination in T. brucei by dephosphorylating the Pol II large subunit, leading to readthrough transcription and pervasive genome transcription.

3 citations

experimental assay

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