Author

Jan Peter Erzberger

The University of Texas Southwestern Medical CenterORCID 0000-0002-0266-8835Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Victor Emmanuel CruziD· 2 shared Arin B. AuroraiD· 1 shared Ashley Leach· 1 shared Christine S. WeirichiD· 1 shared Deepak NijhawaniD· 1 shared Divya ReddyiD· 1 shared Holly H. Guo· 1 shared Jef K. De BrabanderiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Victor Emmanuel CruzORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 31, 2025

A small molecule inhibitor of NVL suppresses tumor growth by blocking ribosome biogenesis

Holly H. Guo, Ye Tao, Victor Emmanuel Cruz…·Deepak Nijhawan

The paper identifies NVL as a target for cancer therapy, showing that its inhibition by MM17 and MM927 suppresses tumor growth through ribosome biogenesis disruption.

DOI 10.1101/2025.07.31.667081

mouseproteomics

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedApr 17, 2024

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor Emmanuel Cruz, Christine S. Weirich, Nagesh Peddada, Jan Peter Erzberger

This study identifies Dbp10/DDX54's role in forming the peptidyl transferase center during 60S ribosome biogenesis using cryo-EM.

15 citations

cryo-EMexperimental assay

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