Author

Sai Manoz Lingamallu

Manipal Academy of Higher EducationORCID 0000-0002-0555-7727Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Arjun GuhaiD· 3 shared Aditya Deshpande· 2 shared Daniel LafkasiD· 2 shared Neelanjana RayiD· 2 shared Neenu Joy· 2 shared Raj K. LadheriD· 2 shared Alessandra Livraghi-ButricoiD· 1 shared Chakenalli N Naveenkumar· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

Arjun GuhaORCID

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3 papers

Recent·Most cited

Cell BiologyLife Science AlliancePeer-reviewedDec 24, 2025

Notch signaling stabilizes lengths of motile cilia in multiciliated cells in the lung

Neenu Joy, Aditya Deshpande, Sai Manoz Lingamallu…·Arjun Guha

This study shows Notch signaling stabilizes ciliary lengths in lung multiciliated cells, with environmental factors like M. tb infection altering this regulation.

3 citations

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintNov 24, 2025

Notch and Wnt signalling interact for proper prosensory and non-sensory domain formation

Neelanjana Ray, Sai Manoz Lingamallu, Arjun Guha, Raj K. Ladher

This study identifies a non-canonical Notch-Wnt interaction that maintains prosensory domain identity by regulating Sox2 and Lmx1a through NICD-mediated suppression of Wnt activity.

DOI 10.1101/2025.11.24.690138

mouseexperimental assay

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Cell BiologyCell ReportsPeer-reviewedAug 24, 2024

NEUROEPITHELIAL BODIES AND TERMINAL BRONCHIOLES ARE NICHES FOR DISTINCTIVE CLUB CELLS THAT CAN REPAIR AIRWAYS FOLLOWING ACUTE NOTCH INHIBITION

Sai Manoz Lingamallu, Aditya Deshpande, Neenu Joy…·Arjun Guha

This study investigates how Notch inhibition affects airway club cells, showing that a subpopulation can repair airways by reverting to a progenitor state.

6 citations

mousebulk RNA-seq

𝕏 PostBluesky