Shiheng Liu

This study identifies RBM5's role in regulating splicing by activating DHX15 and blocking spliceosome progression, with implications for cancer-related splicing dysregulation.

This study uses cryoET and deep learning to reveal structural differences in the tegument and envelope of EBV and KSHV virions compared to other herpesviruses.

The paper humanizes yeast U1 snRNP components to study 5 ss recognition, finding that U1C ZnF substitution causes splicing defects and mitochondrial dysfunction.

The paper reports cryoEM structures of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney, revealing structural differences and insights into their organization.